Identifying primary site of lung-limited Cancer of unknown primary based on relative gene expression orderings
نویسندگان
چکیده
منابع مشابه
Cancer of unknown primary site.
Copyright © 2014 Massachusetts Medical Society Cancer of unknown primary site is a heterogeneous group of cancers for which the anatomical site of origin remains occult after detailed investigations.1,2 The emergence of sophisticated imaging, immunohistochemical testing, and molecular-profiling tools has influenced our approach to unknown primary cancer, although it has also increased the ambig...
متن کامل[Metastatic cancer of unknown primary site].
The history, physical examination, radiographic and laboratory studies and histological diagnosis must be completely evaluated to search for the primary tumor. For diagnosis of cervical lymph node metastasis, not only whole body examination but also head and neck examination is important in which quadrascopy (nasopharyngeal, laryngeal and esophageal fiberoscopy and bronchoscopy) must be perform...
متن کاملAdenocarcinoma of Unknown Primary Site
BACKGROUND Metastatic cancer of unknown primary site occupies 0.5-10% of all diagnosed cancer patients and includes various tumors with diverse responses to systemic chemotherapy. Adenocarcinoma of unknown primary site (ACUPS), the most common subtype, has no standard treatment, rarely responds to conventional treatment and has a poor survival rate. METHODS The retrospective study was perform...
متن کاملCancer of unknown primary or unrecognized adnexal skin primary carcinoma? Limitations of gene expression profiling diagnosis.
TO THE EDITOR: Chiang et al are correct that gene expression profilinginpatientswithcancerofunknownprimary(CUP)canbeuseful and in some instances complements immunohistochemistry in determining the primary cancer site or tissue of origin in these patients. However, thecasepresentedisprobablynotCUP,but illustrateswelloneof the limitations of gene expression profiling in patients with suspected CU...
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ژورنال
عنوان ژورنال: BMC Cancer
سال: 2019
ISSN: 1471-2407
DOI: 10.1186/s12885-019-5274-4